Bilateral Breast Coil

This Bilateral Breast coil for 7 T is a proton phosphorus coil, it has a 4 channel dual tuned transceiver and a 28th channel receiver. It has comfortable pillows to support the patients body and it has a special headrest to support ones head.

It can be interfaced to a single transmit and multi-transmit systems.

This breast coil has been made to improve diagnostics and response monitoring. It has been used in research in different parts of the world.


High quality bilateral MRI [3] and 31P MRSI obtained with the new breast coil at 7T [4]. High resolution MRI can be obtained at high SENSE factors resulting in 0.5mm isotropic and 1 minute temporal resolution revealing blood kinetics even in spiculations of the tumor. At the same scan session, sensitivity optimized 31P MRSI can be obtained to image cell membrane metabolism.

Courtesy figure: Boer, van der Velden, Bank et al. University Medical Center Utrecht, the Netherlands

See below for references.


References obtained with this coil or its earlier version:

19. Radiofrequency configuration to facilitate bilateral breast 31 P MR spectroscopic imaging and high-resolution MRI at 7 Tesla. van der Velden TA, Italiaander M, van der Kemp WJ, Raaijmakers AJ, Schmitz AM, Luijten PR, Boer VO, Klomp DW. Magn Reson Med. 2014 Dec 17.

18. Optimization of 7-T Chemical Exchange Saturation Transfer Parameters for Validation of Glycosaminoglycan and Amide Proton Transfer of Fibroglandular Breast Tissue. Dula AN, Dewey BE, Arlinghaus LR, Williams JM, Klomp D, Yankeelov TE, Smith S. Radiology. 2014 Oct 29:140762

17. Tilt optimized flip uniformity (TOFU) RF pulse for uniform image contrast at low specific absorption rate levels in combination with a surface breast coil at 7 Tesla. van Kalleveen IM, Boer VO, Luijten PR, Klomp DW. Magn Reson Med. 2014 Aug 26.

16. Increased sensitivity of 31P MRSI using direct detection integrated with multi-echo polarization transfer (DIMEPT). van der Kemp WJ, Boer VO, Luijten PR, Klomp DW. NMR Biomed. 2014 Oct;27(10):1248-55

15. MRI and 31 P magnetic resonance spectroscopy hardware for axillary lymph node investigation at 7T. Rivera DS, Wijnen JP, van der Kemp WJ, Raaijmakers AJ, Luijten PR, Klomp DW. Magn Reson Med. 2014 Jun 5

14. Requirements for static and dynamic higher order B0 shimming of the human breast at 7 T. Boer VO, Luttje MP, Luijten PR, Klomp DW. NMR Biomed. 2014 Jun;27(6):625-31.

13. (31)P magnetic resonance spectroscopy of the breast and the influence of the menstrual cycle. Stehouwer BL, van der Kemp WJ, Luijten PR, van den Bosch MA, Veldhuis WB, Wijnen JP, Klomp DW. Breast Cancer Res Treat. 2014 Apr;144(3):583-9.

12. Detecting breast microcalcifications with high-field MRI. de Leeuw H, Stehouwer BL, Bakker CJ, Klomp DW, van Diest PJ, Luijten PR, Seevinck PR, van den Bosch MA, Viergever MA, Veldhuis WB. NMR Biomed. 2014 May;27(5):539-46.

11. Dynamic contrast-enhanced and ultra-high-resolution breast MRI at 7.0 Tesla. Stehouwer BL, Klomp DW, van den Bosch MA, Korteweg MA, Gilhuijs KG, Witkamp AJ, van Diest PJ, Houwert KA, van der Kemp WJ, Luijten PR, Mali WP, Veldhuis WB. Eur Radiol. 2013 Nov;23(11):2961-8

10. Amide proton transfer imaging of the human breast at 7T: development and reproducibility. Klomp DW, Dula AN, Arlinghaus LR, Italiaander M, Dortch RD, Zu Z, Williams JM, Gochberg DF, Luijten PR, Gore JC, Yankeelov TE, Smith SA. NMR Biomed. 2013 Oct;26(10):1271-7.

9. Adiabatic multi-echo ³¹P spectroscopic imaging (AMESING) at 7 T for the measurement of transverse relaxation times and regaining of sensitivity in tissues with short T₂ values. van der Kemp WJ, Boer VO, Luijten PR, Stehouwer BL, Veldhuis WB, Klomp DW. NMR Biomed. 2013 Oct;26(10):1299-307

8. Intramolecular zero-quantum-coherence 2D NMR spectroscopy of lipids in the human breast at 7 T. de Graaf RA, Klomp DW, Luijten PR, Boer VO. Magn Reson Med. 2013 Mar 6. doi: 10.1002/mrm.24701. [Epub ahead of print]

7. 7 T versus 3T contrast-enhanced breast magnetic resonance imaging of invasive ductulolobular carcinoma: first clinical experience. Stehouwer BL, Klomp DW, Korteweg MA, Verkooijen HM, Luijten PR, Mali WP, van den Bosch MA, Veldhuis WB. Magn Reson Imaging. 2013 May;31(4):613-7.

6. Ultra high spatial and temporal resolution breast imaging at 7T. van de Bank BL, Voogt IJ, Italiaander M, Stehouwer BL, Boer VO, Luijten PR, Klomp DW. NMR Biomed. 2012 Oct 18

5. Quantitative 31P magnetic resonance spectroscopy of the human breast at 7 T. Wijnen JP, van der Kemp WJ, Luttje MP, Korteweg MA, Luijten PR, Klomp DW. Magn Reson Med. 2012 Aug;68(2):339-48

4. Increase in SNR for 31P MR spectroscopy by combining polarization transfer with a direct detection sequence. van der Kemp WJ, Boer VO, Luijten PR, Wijnen JP, Klomp DW. Magn Reson Med. 2012 Aug;68(2):353-7.

3. Direct B0 field monitoring and real-time B0 field updating in the human breast at 7 Tesla. Boer VO, van de Bank BL, van Vliet G, Luijten PR, Klomp DW. Magn Reson Med. 2012 Feb;67(2):586-91

2. 31P MRSI and 1H MRS at 7 T: initial results in human breast cancer. Klomp DW, van de Bank BL, Raaijmakers A, Korteweg MA, Possanzini C, Boer VO, van de Berg CA, van de Bosch MA, Luijten PR. NMR Biomed. 2011 Dec;24(10):1337-42.

1. Feasibility of 7 Tesla breast magnetic resonance imaging determination of intrinsic sensitivity and high-resolution magnetic resonance imaging, diffusion-weighted imaging, and (1)H-magnetic resonance spectroscopy of breast cancer patients receiving neoadjuvant therapy. Korteweg MA, Veldhuis WB, Visser F, Luijten PR, Mali WP, van Diest PJ, van den Bosch MA, Klomp DJ. Invest Radiol. 2011 Jun;46(6):370-6.